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Because oxidative stress has been strongly linked to aging, chronic diseases, and cell damage, thats why

However, the most common manifestations are seen in the lungs ranging from mild pneumonia to more severe presentation associated with acute respiratory distress syndrome, shock, respiratory failure [2,3]

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At the matrix level, abundant deposition of extracellular matrix (ECM) components and sustained activation of cancer-associated fibroblasts (CAFs) densify the stroma and create major physical barriers to the diffusion of nanoparticles and macromolecules [30, 32, 34]

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