H.BreunisH.TimilshinaN.JohnstonC.TomlinsonG.TannockI.et al (2010)
After 6 months, your provider must submit for reauthorization
Heller RS, Kieffer TJ, Habener JF
doi: 10.1155/2016/1624643
In addition, the effects of renal insufficiency on sitagliptin pharmacokinetics in patients with type 2 diabetes and mild or moderate renal insufficiency were assessed using population pharmacokinetic analyses

if you become pregnant whilst on treatment, stop the medication and seek immediate medical and nutritional review [1] [25] Contact your GP urgently if you experience: Severe, persistent abdominal pain (with or without vomiting) which could indicate pancreatitis Upper-right abdominal pain, fever or jaundice which may suggest gallbladder disease Persistent nausea or vomiting preventing adequate nutrition Signs of dehydration (dark urine, dizziness, reduced urination) Unexplained symptoms such as jaundice, severe fatigue, or mood changes For people with diabetes: hypoglycaemia (low blood sugar) symptoms when taking insulin or sulfonylureas alongside GLP-1 therapy Regular monitoring throughout GLP-1 treatment should include periodic assessment of weight, body composition where possible, nutritional intake, and relevant blood markers