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The TRIUMPH-4 Phase 3 trial confirmed this: at 68 weeks, mean weight loss had reached 28.7% at 12 mg, an additional 4.5 percentage points beyond the 48-week Phase 2 result

Low blood sugar may occur if these weight management medications are taken in addition to glucose-lowering drugs that can cause hypoglycemia (eg, insulin or a sulfonylurea)

Therefore, clinicians must set realistic expectations when initiating GLP-1based adjunct treatment in type 1 diabetes

Monthly weight loss during this period often runs 4-6% of remaining body weight

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GLP-1, or glucagon-like peptide-1, is a hormone that plays a key role in regulating blood sugar levels and appetite