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Injecting in a post-absorptive state keeps the signaling environment cleaner and consistent across all 10 doses

Conclusion Our data indicate that hGrx1-roGFP2 is a sensitive and reliable biosensor for assessing and quantifying real-time changes in the cytosolic glutathione redox potential of the malaria parasite Plasmodium falciparum

For instance chlorpromazine and chloroquine have been shown to inhibit the lysosomal phopholipases A1 in vitro [33,34] and a time- and dose-dependent down regulation of acid ceramidase was also observed for desipramine, chlorpromazine, and chloroquine [35]