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The pharmacological efforts to treat schizophrenia have for many years largely focused on dopamine 2 receptor antagonism, which constitutes the primary mediatior of antipsychotic effect of efficacious drugs [3, 4]

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10.1186/1749-8546-4-6 153 ZhengQ.ZhuJ

VPS35, a component of the retromer complex, contributes to mitochondrial fragmentation and impaired trafficking, particularly affecting dopaminergic neurons (Franco et al., 2021

Statements Data availability statement The datasets presented in this study can be found in the article/ Supplementary Material