10.1016/j.neuint.2024.105738 170 MohebaliN.Shahzadeh FazeliS
Several nanoparticles with enhanced delivery abilities have been developed as well, which includes those attached to the silica core protected by poly(ethylene glycol) chains (PluSNO), CdSe quantum dots, rotaxane-branched radical dendrimers (Gn-TEMPO), G4-polyamidoamine dendrimers, 3Gc0T zero-generation dendrimer, polyurethane dendrimers, gold nanoparticles, liquid crystal nanoparticles, nanosized sterically stabilized liposomes, poly[oligo(ethylene glycol)methyl ether acrylate] and poly(2-hydroxyethyl acrylate) conjugates, and redox nanoparticles
[1] [2] 64-Fold Bioavailability Is a Structural Achievement The 64-fold increase in plasma glutathione levels versus conventional oral glutathione is a direct consequence of phospholipid membrane architecture
The difference between patients who push through and those who quit isn't willpower
This study documented in humans the variability of the leak pathway in response to systemic inflammation versus the constancy of the pore pathway, and that very large solutes cannot penetrate the paracellular barrier, even in the presence of inflammation
Also, LS ameliorated the raised levels of pro-inflammatory markers (NF-k, IL-1, IL-6, and TNF-), and the expression level of NF-k improving the renal and testicular function in rats with diabetic nephropathy induced by streptozotocin 60,79
