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We will examine the role of L-glutamine in health and propose how the extra-erythrocytic functions of L-glutamine might contribute to its beneficial effects in SCD

No exclusion criteria were set based on sex, age ethnic or cultural background

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A minimum quantity of 20,000 cells per sample was collected, and the DNA histograms were further analyzed using the ModFit LT software (Verity Software House, Topsham, ME, USA) for cell cycle analysis

OSGIN1 can promote apoptosis [58, 59] or autophagy [60] and cytoprotection [61]