Enhance immune health
This is the change your patients describe when they tell you, "my skin is just different now" or "my hair won't grow back the way it used to." The second story is less well-known
Glutathione, a powerful antioxidant, is important in detoxification, immune support, and cellular health
Among them, the glutamate produced by the decomposition of glutamine via GLS not only provides the raw material for the synthesis of GSH but is also further metabolized into -ketoglutarate (-KG) in the mitochondria under the action of glutamate dehydrogenase (GLUD1) or transaminases and then enters the tricarboxylic acid cycle to produce ATP [29]
J Biol Chem 271:1902119024 [DOI] [PubMed] [Google Scholar] Keith DE, Anton B, Murray SR, Zaki PA, Chu PC, Lissin DV, Monteillet-Agius G, Stewart PL, Evans CJ, von Zastrow M
Subdermal application overcomes this barrier and directly reaches the deeper layers of the skin, resulting in higher absorption and efficacy