Insulin degludec is not usually described as directly damaging kidney tissue
In primary human satellite cells isolated from vastus lateralis biopsy (Pax7+ FACS-sorted, passage 1), MGF-Ct24E (100 nM, 48 h) increases BrdU+ proliferating cells from 28% to 44% (p 1 M vs native IGF-1 K_d ~1 nM for IGFBP-3)
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Cummings DE, Weigle DS, Frayo RS, Breen PA, Ma MK, Dellinger EP, et al
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These responses, which stand slightly above 135,075 to slightly below 135,793, are proportional to the signal elicited by the HPLC system in D-Carnitine for each injection