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As discussed in the earlier sections of this review, the molecular mechanisms of the inhibitors have been proposed on the basis of the reaction kinetics and structural analyses

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Cell 51, 575586

And during the menopausal transition, several things set us up for higher cortisol levels, such as not getting enough sleep, relying too much on caffeinated beverages for energy, drinking more alcohol, and experiencing flip-flopping mood changes as well as the anxiety that comes from dealing with hot flashes

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