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The shedding typically begins three to six months after the onset of rapid weight loss and resolves within six to twelve months as the body adapts to its new metabolic equilibrium

22 The initial dose is 1500 mg/m, dissolved in 100 ml of normal saline or 5% glucose injection, and administered via intravenous infusion over 15 minutes

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These build upon similar work using ex vivo organotypic slices and 2D cancer cell co-culture [14, 163]

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