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Clinical studies consistently show substantial weight loss outcomes in patients using GLP-1 medications, often accompanied by improvements in blood sugar control, cholesterol levels, and decreased cardiovascular risks

At the same time, a pooled review of clinical trials found no significant overall increase in kidney injury

Diabetes Research and Clinical Practice

BID, twice a day

Recent studies suggest that treatment with semaglutide (GLP-1RA) in combination with firsocostat (ACC-a inhibitor) and/or cilofexor (nonsteroidal FXR agonist) can further improve hepatic steatosis and thus NAFLD compared with semaglutide alone in exploratory efficacy analyses [113]

Steroid injections only made things worse, and no matter how hard I tried, I couldnt lose the weight like I used to