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It is naturally present in breast milk and has minimal transfer to infants

Cagrilintide was initiated at 0.3 mg for the 0.3 mg group, or 0.6 mg for all higher-dose groups and escalated every two weeks until reaching the final dose

To investigate the application of this stapling methodology in biologically active peptides, an i,i + 4 -stapled Axin mimetic 10 developed by the Verdine group using ring-closing metathesis (RCM) (Grossmann et al., Figure 4)

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