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A clinical study involved middle-aged and older adults on a low-calorie diet

Why this trial matters: First bispecific + CD38 combo to show superior PFS and OS in Phase III in RRMM Potential new standard of care as early as second-line Demonstrates deep responses, high MRD-negativity, and durable outcomes First-line Strategies in BRAF V600E-Mutant mCRC: Real-World Evidence Signals Treatment Priorities In a real-world retrospective cohort of patients with BRAF V600E-mutant metastatic colorectal cancer (mCRC), frontline chemotherapy plus anti-VEGF therapy was associated with the longest survival outcomes, while BRAF-targeted strategies showed promising response rates, emphasizing the need for tailored therapy and prospective validation

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To provide timely, complementary evidence, we conducted a comparison of tirzepatide and semaglutide in patients at low, moderate and high cardiovascular risk who were diagnosed with obesity and type 2 diabetes and subgroups with specific cardiovascular conditions

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On the other hand, it has also been observed that patients with obesity have a chronic inflammatory state of low grade (59)