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However, overexpression of adiponutrin has no effect on TAG hydrolysis in 293 HEK cells, in contrast to desnutrin/ATGL and other patatin domaincontaining proteins that increase TAG hydrolysis in these cells (62)

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Mechanism & Rationale: Survodutides dual agonism aims to combine the satiety and glycemic benefits of GLP-1 receptor activation with enhanced metabolic rate and liver effects via glucagon receptor stimulation

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