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The reaction is typically carried out under controlled conditions, including precise temperature and pH regulation, to ensure optimal conversion rates

In the future, high-quality research needs to be further carried out to clarify its clinical positioning and safety, so as to promote its rational application in digestive system diseases

This is achieved via the increased oxygen uptake by colonocytes which then promotes epithelial hypoxia thereby supporting the anaerobic lifestyle of many important bacteria present in the intestinal mucosa (Itoh and Freter 1989

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Compare with Retatrutide (adding glucagon receptor) and Cagrilintide (amylin agonist) for mechanistic pathway comparisons