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This article is part of our series on the FDAs National Priority Voucher program, exploring the therapies selected, their potential impact, safety considerations, and what accelerated review could mean for patients in the US and globally

Some patients prefer evening or bedtime administration, while others prefer morning

That said, tolerability is broadly similar across the three compounds: gastrointestinal adverse events dominate, and slow titration is the universal strategy for managing them

Indians, meanwhile, have simply been watching this from the sidelines.Thats because the latest formulations, Novo Nordisk A/Ss Ozempic and Wegovy and Eli Lilly & Cos Mounjaro and Zepbound, wont be available in India anytime soon, amid global supply shortages

As a result, interpretations regarding skeletal muscle preservation or loss must be made with caution, particularly in the absence of direct assessments of muscle strength or function

S., Hammer, M., Zychma, M