Experts say patients taking GLP-1-based medications should monitor for mood changes and report symptoms such as: New or worsening depression Anxiety or emotional changes Suicidal thoughts More research is needed to determine whether these drugs directly affect mood or whether changes are related to factors such as rapid weight loss, hormonal changes or other metabolic effects
However, for qualified patients, they may help support appetite control, earlier fullness, reduced food intake, and greater consistency with a medical weight-loss plan
J Clin Endocrinol Metab (2015) 100(3):96876.10.1210/jc.2014-3144 144 SeimonRVBrennanIMRussoALittleTJJonesKLStandfieldSet alGastric emptying, mouth-to-cecum transit, and glycemic, insulin, incretin, and energy intake responses to a mixed-nutrient liquid in lean, overweight, and obese males
But, McIntyre cautions, despite these encouraging preliminary results, these medications are not proven psychiatric treatments, and they are not ready for prime time
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