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4.3 Targeting CSCs through coordinated pathway disruption SFN demonstrates remarkable efficacy against CSCs through its ability to simultaneously disrupt multiple signaling pathways that maintain stemness and self-renewal capacity

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To view digital features for this article go to Introduction The last estimates from the International Diabetes Federation (IDF) atlas indicated a sustained and still alarming increase in the global prevalence of diabetes from 9.3% (463 million cases) in 2019 to an expected 10.9% (700 million cases) in 2045 [1]