Starting at higher doses substantially increases side effects like nausea and digestive issues
Proper hydration can help keep this at bay
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CrossRef Citri Grandis Exocarpium with medicine and food homology: A review regarding its potential anti-obesity effects and future applications Peng-fei Li, Yuan-yun Du, Shao-long Zheng, Zheng-ming Qian, Jin-lin Zhou, Zhi-shu Huang, Yuan-jia Hu Journal of Ethnopharmacology.2026
It increases the risk for multiple metabolic complications including type 2 diabetes (T2D), metabolic-dysfunction associated steatotic liver disease (MASLD, previously known as non-alcoholic fatty liver disease), cardiovascular disease as well as many mechanical complications such as osteoarthritis and obstructive sleep apnoea (OSA) [3]
Generics were able to get the green light after Novo Nordisk's regulatory exclusivity (new window), which protected it from generic competition, ended in January
