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MolAICal: A soft tool for 3D drug design of protein targets by artificial intelligence and classical algorithm

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Endocrinology 163 , bqab216 (2022)

Rybelsus (semaglutide tablets) [package insert]

Only after the drug has substantially cleared can receptors fully recover without ongoing stimulation

Self-directed drug holidays carry risks, especially for people using GLP-1 medications for diabetes management where blood sugar control may deteriorate during the break