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It reported 22.7% mean weight loss at 68 weeks vs 16.1% for semaglutide alone and 11.8% for cagrilintide alone clear additive benefit

Even more recently completed trials have struggled with diverse enrollmenta Phase 2 trial of crenezumab in Alzheimers disease with 360 participants across 83 sites in 6 countries reported 97.5 percent of participants being white, and only 2.8 percent of all participants being Hispanic, for example (however, women consisted of 55.3 percent of all participants)

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Researchers exploring microdosing GLP-1 for autoimmune conditions are targeting specifically this anti-inflammatory mechanism

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