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Decreased appetite while therapeutically desirable, this can occasionally lead to inadequate nutritional intake if not monitored

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(If a patient is transitioning from another drug for weight loss, healthcare providers can consider their baseline BMI at the start of any drug therapy)

Lancet Diabetes Endocrinol (2020) 8(4):32536

Mitochondrial ATP production primarily involves the five respiratory complexes and two electron carriers that collectively make up the electron transport chain: NADH dehydrogenase, succinate dehydrogenase, coenzyme Q10 (CoQ10)cytochrome C reductase, cytochrome C oxidase, ATP synthase, and the electron carriers CoQ10 and cytochrome C

Although generally considered safe for most people when used appropriately, its safety can depend on the method of use and individual health factors