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Peak plasma concentrations occur 8 to 72 hours after subcutaneous injection, though the medication's 5-day half-life ensures sustained therapeutic effects throughout the weekly dosing interval

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American Journal of Hypertension, 5(12), 1040-1042

le Roux CW, Welbourn R, Werling M, Osborne A, Kokkinos A, Laurenius A, et al