Some concerns include slowed stomach movement, which could affect gastrointestinal health, and rapid muscle loss, which may reduce the bodys ability to burn calories and impact overall health and longevity
Lau J, Bloch P, Schffer L, Pettersson I, Spetzler J, Kofoed J, Madsen K, Knudsen LB, McGuire J, Steensgaard DB, Strauss HM, Gram DX, Knudsen SM, Nielsen FS, Thygesen P, Reedtz-Runge S, Kruse T
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Sarah Garone Author Weight Loss Medications
This represents direct evidence of the mechanism at the cellular level, though its translation to clinical longevity outcomes in humans continues to be studied