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Bioconjugate Chem 25:611617 Chari RVJ (2008) Targeted cancer therapy: conferring specificity to cytotoxic drugs

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Additionally, the dissolution of CaO generates ionic calcium (Ca), which may play a key role in promoting the accumulation of tumor-specific materials via interaction with components of the bone matrix

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NICE and British National Formulary (BNF) guidance recommend 1 mg hydroxocobalamin on alternate days until no further improvement in symptoms is observed