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or history of external thyroid irradiation), or who are taking certain medications (for example, lithium, which interferes with the formation of thyroid hormone precursors), it has been shown that excessive iodine intake may lead to overt or subclinical hypothyroidism, but it is transient and resolves when iodine intake is decreased

However, the poor solubility, limited colonic irrigation retention time, and inadequate colon adhesion of emodin hinder its clinical application

The peptide dissolves quickly and completely

According to NICE Clinical Knowledge Summary guidance, patients with neurological involvement should receive more intensive initial treatment to optimise recovery potential

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