When to Reassess Protocol Signs of Positive Response Improved energy consistency and reduced afternoon fatigue (week 1-4) Faster healing of minor cuts and skin blemishes (week 2-4) Visible skin tone evening reduced dullness, brighter complexion (week 4-8) Declining AST/ALT on bloodwork (week 4-8) Reduced hs-CRP indicating lower systemic inflammation (week 4-8) Nail quality improvements reduced brittleness, improved growth (week 4-8) Signs to Reassess No subjective or objective changes after 8 weeks evaluate delivery route first
Briggman, K
GLP-1 receptors are widely distributed throughout the central nervous system, including brain regions involved in reward processing, motivation, and addictive behaviorsparticularly the mesolimbic dopamine system, which includes the ventral tegmental area and nucleus accumbens
Route and bioavailability
Esmaeili Y, Yarjanli Z, Pakniya F, Bidram E, os MJ, Eshraghi M, Klionsky DJ, Ghavami S, Zarrabi A (2022) Targeting autophagy, oxidative stress, and ER stress for neurodegenerative disease treatment
add at 2448 h