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References: Role of the glutathione antioxidant system in the autophagic process outcome, Yong J

The final "execution" step of necroptosis, MLKL oligomerization, is also under redox control

Yoon WS, Chang JH, Kim JH, Kim YJ, Jung TY, Yoo H, et al

The findings indicated a significant reduction in the proportion of deaths attributable to cardiac causes (195)

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Therefore, this review elucidates the etiology, inducements, pathogenesis and treatment modalities of migraine, the clinical evidence that migraine is associated with oxidative stress and neurogenic inflammation, as well as the experimental evidence of antioxidant and anti-inflammatory effects of topiramate, which is of great significance for further research and exploration of the possible mechanisms of topiramate in the treatment of migraine by modulating oxidative stress and neurogenic inflammatory pathways