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The most common adverse events (AEs) in the Phase 2 study were gastrointestinal (GI) related, including nausea, vomiting and constipation

Mol Nutr Food Res 68:2300419 Khrle J (2023) Selenium, iodine and ironessential trace elements for thyroid hormone synthesis and metabolism

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In people with significant kidney or liver impairment, B6 clearance may be reduced, potentially leading to accumulation at standard doses

However - I've been reading a lot of comments of this lasting for months and months, and since I'm going to the beach in August (!!!!!!!!) I'm going to the doctor this Thursday, and then trying to get referred to a dermatologist