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Claudin-1 regulates intestinal epithelial homeostasis through the modulation of Notch signaling In a series of studies in our and collaborating laboratories (although predominantly using colorectal cancer-originated tissue and cell lines), we have observed an intriguing inverse correlation between claudin-7 and claudin-1 expressions

Ten trials 13,14,2632 had sufficient data for the meta-analysis (n=366 treatment, n=359 control), and five trials 15,26,3335 were excluded from quantitative synthesis due to incomplete or non-extractable data

Potential side effects of IV administration can include more severe reactions like Stevens-Johnson Syndrome (a rare but serious skin disorder) or complications related to the injection site itself

[10] [5] Psychiatric effects must also be considered

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It mimics GLP-1, a natural gut hormone, to regulate blood sugar, increase insulin, suppress appetite, and promote long-term weight loss