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3-Hydroxyanthranilic acid, one of metabolites of tryptophan via indoleamine 2,3-dioxygenase pathway, suppresses inducible nitric oxide synthase expression by enhancing heme oxygenase-1 expression
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The first step is the unusual coupling of the gamma-carboxylic acid of glutamic acid to cysteine by the enzyme gamma-glutamylcysteine synthase to form gamma-glutamylcysteine
Oxidative DNA base damage and antioxidant enzyme levels in childhood acute lymphoblastic leukemia
At 21days post-treatment blood samples (7mls) were obtained from the retro-orbital sinus of each animal after light ether anaesthesia and analyzed for total glutathione, reduced glutathione and glutathione peroxidase activities respectively
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