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For example, IL-27 and small molecules that alter macrophage polarization are under investigation

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Assessments of outpatient compliance with the medication regimen, as well as clinical evaluations and assessments of drug tolerability, were made by a telephone check-in at the end of week 1 and in-person check in at the end of week 4 and week 8, at which time pill counts were performed and plasma SSRI concentrations were assayed