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As mentioned before, free radicals have been found to react with macromolecules (lipids, proteins, DNA) within the cell, with one of the most frequent targets being the polyunsaturated fatty acids that largely comprise the cell membranes

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This is especially important for individuals with absorption issues, such as those with gut inflammation or certain dietary restrictions

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If pain exceeds this time frame then the tendon has been irritated too much and the loading programme need to be reduced