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Drug labeling doesnt list vulvar or vaginal adverse events as defined side effects, based on publicly available prescribing information from the US Food and Drug Administration, which supports that this isnt an official diagnosis (FDA)

It often turns a manageable side effect into a miserable 48-hour experience

There is some evidence in rat studies of reductions in oxidative stress as well as improvements in the function of seminiferous tubules in rats

Loss of E-cadherin enhances IGF1-IGF1R pathway activation and sensitizes breast cancers to Anti-IGF1R/InsR inhibitors

Deeper Sleep and Brighter Moods Carrying extra weight around the neck and midsection can narrow the airway at night, leading to obstructive sleep apnea (OSA)

To gain approval, one has to develop good documentation, he explains