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Semaglutide and tirzepatide have their marketing authorizations, but neither is reimbursed in France for obesity as of May 2026, despite favorable opinions from the French National Authority for Health (HAS)

These medications are used to treat type 2 diabetes and also have skyrocketed in popularity recently as a way to manage weight, which can help prevent to diabetes and other weight-related health conditions

According to Drugs.com, almost 14% of people who try Ozempic don't lose weight

Most people lose one to three pounds in this window, mostly from reduced calorie intake and some water weight

This suggests that a few companies are approving prescriptions for people who do not meet clinical criteria

The phase 2 dose-response was orderly, which is reassuring from a pharmacology standpoint because a clean dose-dependence argues that the effect is real and mechanism-driven rather than an artifact