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If side effects occur, strategies such as slowing the titration schedule, adjusting meal patterns, or making hydration recommendations can help ensure comfort while still allowing progress to continue

Causality is difficult to prove, yet the pattern has made many dermatologists uneasy

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The workflow underscores the importance of considering the additive burden of genetic variants typically classified as benignbeyond the ACMG pathogenicity frameworkfor accurate phenotypic assessment

Pan Y, Nicolazzo JA

2023;142 doi: 10.1016/j.fsi.2023.109086