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J Biosci Bioeng 123:555561

doi: 10.3390/genes14050953 98

Even a low dose LPS challenge of 0.6 ng/kg body weight given intravenously can induce a profound, if transient, 25-fold and 100-fold increase in plasma IL-6 and TNF-alpha, respectively

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However, the role of the microbiome in NNMTi-mediated weight loss is yet to be elucidated