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For instance, participants in clinical trials have experienced weight reductions of 15% or more, which can have profound effects on overall health, including reducing the risk of comorbidities associated with obesity

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[133] have shown that zinc deficiency in mice may lead to ZnT8 depletion and may contribute to perturbed function of the islets of Langerhans and increased of insulin, leading to a greater risk of type 2 diabetes mellitus

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