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This characteristic may improve renal function by increasing renal blood flow, urine flow rate, preventing elevated plasma creatinine, reducing tubular necrosis, increasing renal interstitial fluid and glomerular filtration rate, and cytoprotective and anti-inflammatory effects [12,13], and may improve glomerular hyperosmosis in patients with T2DM in some cases [14]

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This effect was associated with the upregulation of fibrosis-related genes VIM (Fig

This peptide binds to copper ions, forming a complex that enhances the biological activity of copper