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Common possible side effects may include: Vomiting Dizziness Dry mouth Trouble sleeping Irritability More serious side effects can include: Increased risk of suicidal thoughts in some young adults Seizures Increase in blood pressure and heart rate Chest pain Allergic reactions, including rashes or anaphylaxis Angle-closure glaucoma Risk of opioid overdose Sudden opioid withdrawal Liver damage or hepatitis Increased risk of low blood sugar levels in patients taking type 2 diabetic medication You should call your doctor if you notice any of these adverse effects or unusual behavior changes
Okawa M, Mishima K, Nanami T, et al
The article attributes that position to current guidance from obesity and cardiology societies, though it never names the specific guidelines it means
This is the same pathway that resistance training activates, which is why combining IGF-1 LR3 with training can produce synergistic effects
While gastrointestinal side effects are common with this medication class, blood in the stool is not listed as a typical adverse effect in the FDA prescribing information for either Mounjaro or Zepbound