Mol Psychiatry 29(8):25712574 Mandal PK et al (2022) Schizophrenia, bipolar and major depressive disorders: overview of clinical features, neurotransmitter alterations, pharmacological interventions, and impact of oxidative stress in the disease process
pylori associated peptic ulcer disease, pancreatic cancer, metabolic associated steatotic liver disease (MASLD), constipation and inflammatory bowel disease
10.1038/ncomms16043 Nat
Biweekly dosing maintains elevated plasma methionine concentrations for 72+ hours per injection, creating overlapping metabolic windows that sustain hepatic lipid export throughout the week
Louis Aronne is a paid consultant and advisory board member for Eli Lilly and Company, the study sponsor and the manufacturer of orforglipron and tirzepatide.
The once-weekly injections are some of the newest out on the market