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DOI: 10.1186/s12876-017-0652-3

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Biomarkers-Guided Metformin-Responsive Treatment in Neurological Diseases Given that most neurological disorders have a complex etiology in their pathophysiology and are influenced by various risk factors such as aging, lifestyle, genetics, and environmental exposure, past clinical interventions directed at a fit-for-all therapy to treat neurodegenerative diseases seem to be less effective (Syal and Wang, 2021)

The neurons in the affected network compensate for this weak or absent signals by increasing the number of neuro-transmitter receptors

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Br J Ophthalmol 100(11):15421546