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Significant yellowing, browning, or any other color change suggests chemical degradation has occurred

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Stress Response and Anxiolytic Models: In rodent elevated plus-maze, open-field, and restraint-stress models as well as small human trials, DSIP reduced behavioral signs of anxiety, lowered plasma cortisol/ACTH responses to stress, and normalized stress-induced alterations in catecholamine and serotonin turnover