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Accessed Jan 19, 2026 at Yanovski SZ, Yanovski JA

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Vitamin C contributes to immune defense by supporting various cellular functions of both the innate and adaptive immune system, according to a 2017 study published in Nutrients

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Extremely high plasma glycine concentrations may lead to hyperglycinemia and, via catabolism, hyperammonemia, potentially causing neurological symptoms such as headache or confusion-though such events are exceedingly rare outside massive irrigant absorption

Accordingly, disrupted interactions between the gut microbiota and bile acids impair intestinal barrier function and activate inflammation-related signaling pathways, exacerbating the progression of IBD