The 8 mg group hit 22.8% weight loss
The causes of bad breath are wide reaching but the condition is often linked to poor dental plaque removal
Statins also increase the expression of tissue-type plasminogen activator (t-PA) (57) and inhibit the expression of endothelin-1, a potent vasoconstrictor and mitogen (58)
However, as explained by the Alzheimers Drug Discovery Foundation in 2024, while urolithin A does have an impressive safety profile, its long-term safety has yet to be established.4 Also, while rare, some people can be allergic to pomegranates, which are rich in the polyphenols that are metabolized into urolithin A.21 This doesnt necessarily mean that those with pomegranate allergies will have a reaction to urolithin A supplements, but it could be something to keep in mind
Sources: Novo Nordisk NovoCare and Eli Lilly LillyDirect self-pay pricing (mid-2026)
J Thyroid Res (2012) 2012:302537.10.1155/2012/302537 57 EffraimidisGWiersingaWM