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The FLOW trial, the first dedicated kidney outcomes trial designed specifically to evaluate a GLP-1 medicine in people with chronic kidney disease and type 2 diabetes, was stopped early because an independent monitoring committee determined that clear evidence of benefit had already emerged.[11] In clinical research, trials are rarely stopped early

A further 50% increase from 10 mg to 15 mg added under 10%

This method bypasses the digestive system, potentially leading to faster and more noticeable results

The article says the beyond-use date is set by the licensed 503A compounding pharmacy from its own stability testing, and documented based on the formulation, container, storage conditions, and published stability data

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doi: 10.1111/j.1600-0846.1998.tb00081.x