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Not only did more than 50% of the participants in a research study lose 15% of their body weight, up to 40% of participants lost up to 20%

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Several serious conditions can initially present with moderate to severe nausea and vomiting

Inflammatory cytokines, such as TNF-alpha and IL-6, interfere with insulin signaling and contribute to insulin resistance

Discontinuation of the drug often leads to recovery of taste sensation

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