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Pulsatile GH signals also activate organ-specic second messenger signaling pathways, such as the Signal Transducer and Activator of Transcription 5B (stat5B) in the liver, with subsequent induction of specic genomic responses in relevant target tissues

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Furthermore, TGP exhibited the potential to decrease the proliferation of keratin-forming cells

Front Endocrinol (Lausanne) 13