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2019, pp

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6 For adults with heart disease and obesity or overweight, along with a reduced-calorie diet and increased physical activity

In humans, neuroimaging studies show associative evidence that GLP-1 agonists alter brain responses to food cues, potentially dampening the neural reactivity to appetizing foods that may trigger binge episodes in susceptible individuals

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Additionally, GLP-1 promotes the growth and proliferation of pancreatic cells, inhibits glucagon secretion, and enhances glucose uptake in peripheral tissues, making it a crucial factor in maintaining blood glucose stability